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Overweight or obesity (BMI 30-plus, or 27-plus with a weight-related condition) where weight loss is the goal and there is no diabetes driving the choice

Serum B12 and a full blood count should be checked when macrocytosis or anaemia is identified alongside an unexpected HbA1c result

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At the end of the 10-week trial, those receiving acetyl-L-carnitine had improvements in depression, musculoskeletal pain, and quality of life scores

B12 is essential for the formation of red blood cells, DNA synthesis, and the proper functioning of the nervous system