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Cell 85 , 707720 (1996)

DANTE INTERNATIONAL S.A

Filtering of quantifiable proteins and missing values imputation were done as in the discovery untargeted analysis

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Furthermore, studies have shown that ovarian cancer cells with elevated levels of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme that catalyzes the conversion of tryptophan to l-kynurenine (Kyn), exhibit platinum resistance by downregulating the ROS/p53 pathway (82)