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All PTZ exposures were recorded and the behavior was analyzed by researchers blinded to treatments in the software BORIS (Friard & Gamba, 2016)

The probiotic strain Bifidobacterium lactis has been shown to protect cultured gut epithelial cells from damage induced by gluten, possibly by blocking gluten-induced increases in intestinal permeability (Lindfors 2008)

In addition to the above drugs, small molecule drugs such as Dihydromyricetin (DHM) (Liang et al., 2014

110,111 Preclinical data indicate that SIRT1 activators, such as resveratrol and SRT1720, improve insulin tolerance by activating the AMPK/IRS-1/Akt pathway, inhibiting FOXO1, 112 and downregulating phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression

ZnC acts as an anti-inflammatory and antioxidant agent