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Studies have shown that after MV treatment in PCOS rats, the levels of D-glucose-6-phosphate, lactate, and GTP were significantly increased, while pyruvate levels were reduced, indicating that MV can improve metabolic disturbances in PCOS patients by restoring glycolysis and glucose metabolism

In addition, DFO has difficulty crossing the blood-brain barrier (BBB), which can now be addressed by intranasal administration of DFO nanoparticles (Crapper McLachlan et al., 1995

By outlining a structured approach through the Longevity Pyramid, it highlights the significance of integrating (i) early diagnostics, (ii) preventive strategies, (iii) lifestyle modifications, (iv) and advanced therapeutic interventions to promote healthy aging and extend lifespan

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These findings provide novel mechanistic insights into potential therapeutic strategies for breast cancer