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Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

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To maintain amino acid nutrition for tumor growth, the expression of the LAT1 ( SLC7A5 ) transporter is controlled by the pro-carcinogenic transcription factors c-Myc (Yue et al., 2017), HIF2 (Elorza et al., 2012), and NOTCH (Grzes et al., 2017), as well as the post-transcriptional regulator miR-126 (Miko et al., 2011)

10.1155/2011/908185 23 KowalczukA.BourebabaN.Kornicka-GarbowskaK.TurlejE.MaryczK.BourebabaL

Neuron 39(6):889909 Lees AJ, Hardy J, Revesz T (2009) Parkinsons disease Lancet Lond Engl 373:20552066 Graham JM, Paley MN, Grnewald RA, Hoggard N, Griffiths PD (2000) Brain iron deposition in Parkinsons disease imaged using the PRIME magnetic resonance sequence