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Amlodipine forms specific polar interactions (hydrogen bonds) with key amino acid residues in the active sites of enzymes

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GGT also identifies liver and brain dysfunction tied to poor diet, alcohol, tobacco, and inactivity

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Overall, we expect our Drug-ID/isASO-ID protocols to work for other classes of ON drugs, too 1,8 , including splice-switching ASOs, siRNAs, antimiRs and ADAR-recruiting ASOs 51