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doi: 10.1002/art.10278 20 MillardTPKirkARatnavelR

Its deficiency can lead to a specific type of anemia called megaloblastic anemia, characterized by the production of abnormally large and dysfunctional red blood cells

Single-cell RNA-sequencing data from adult and pediatric glioblastoma tumors 45 was downloaded from the Broad institute single cell portal ( Cell assignment labels were taken from the original publication

Under iron-deficient conditions, IRPs suppress the translation of these proteins, increasing labile iron pools and sensitizing cells to ferroptosis through enhanced lipid peroxidation [64]