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Linaclotide is a 14amino acid peptide agonist of guanylate cyclase-C used for IBS-C and chronic idiopathic constipation, with multiple phase 3 trials supporting efficacy and safety

doi:10.1080/13697130500118100 2

Additionally, cancer cells undergo metabolic reprogramming to provide the energy and substrates necessary for their rapid proliferation and survival [319]