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Multiple elements of cellular response pathways, such as receptors, adaptors, signal transducers, or transcription factors, are modified and controlled by the ubiquitination system, which thus manages stresses, repairs damages, and restores homeostasis

J Vet Med Sci 78:15571561 Ojelabi OA, Lloyd KP, De Zutter JK, Carruthers A (2018) Red wine and greeen tea flavonoids are cis-alosteric activators and competitive inhibitors of glucose transporter 1 (GLUT1)-mediated sugar uptake

The synthesis of Glu is highly dependent on mitochondrial metabolism, particularly through the TCA cycle, which generates -ketoglutarate (-KG), a key substrate for Glu biosynthesis