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Demonstrating perfect causality is impossible to fulfill (Vega, 2021), but providing a framework in which the question of AD etiology including MAD and where other theories can be incorporated is proposed in Figure 3

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With B12 injections, you can finally restore normal levels of B vitamins that are immediately available to the body, which can in turn elevate your mood, increase your energy, and help you feel more focused

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That effect is well-supported by exercise-dehydration research and is generally small under everyday conditions, but becomes more meaningful in heat, at altitude, after exercise, or during illness