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The NHS advises that taking up to 2 mg (2000 micrograms) daily in supplements is unlikely to cause harm

Given its direct role in cellular metabolism and nerve repair, Methylcobalamin emerges as the preferred choice for patients requiring targeted B12 support

The solution might be to change the medication or add B12 supplements

Whatever you do notice tends to be minor and passing, a touch of tenderness where the needle went in, being the usual one

The AOD 9604 trials did not report responder rates in the same way, but the modest average effect suggests a much lower percentage of participants experienced noticeable changes