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Belo: Well, I have learned that you should take a person as a whole being

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K.Tayanloo-BeikA.ShahbazbadrA.YavariH.NamaziN.et al (2022)

Impaired mitochondrial function due to the downregulation of nuclear-encoded genes involved in oxidative phosphorylation increases ROS production, which in turn phosphorylates the serine residues of insulin receptors and IRSs, thereby resulting in SLCI and a reduction in IR