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In vivo intrastriatal injection of -syn oligomers in experimental animals led to deficits in visuospatial learning, in association with reduced expression of GluN2A NMDA receptor subunit, indicating a selective targeting by -syn oligomers both ex vivo and in vivo [106]

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However, some individuals can suffer a serious setback such as a seizure even weeks later

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rash, urticaria, or anaphylaxis) to vitamin B or to the excipients in the injection should not receive this therapy