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Because they act on two different pituitary receptors that converge on GH release

Whether they gave the peptide body-wide or delivered it directly to the kidneys, it reduced the movement of immune cells into the kidneys, resolved inflammation and damage and improved kidney function, without increasing blood pressure, they report in the journal Kidney International

Zhou F, Zhang H, Cong Z, et al

I no longer went to the gym if my schedule allowed it, but I made fitness a part of my schedule

Thus, these approaches limit their efficacy which wanes after extended use, indicating that use of specific hormones within the GH neuroendocrine axis for somatic benefits of GHRT should be weighed against their dysfunctional, physiological/neuroendocrine potential