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The inhibitory effect of zinc supplementation on M2 polarization suggests benefits for the treatment of M2-dominated conditions, such as allergic asthma, or, more commonly observed in the aging population, cancer [225]

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(2015) compared peripheral blood mRNA expression in patients with early-stage PD to healthy subjects

Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities