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It facilitates deamidation, where asparagine and glutamine residues convert into different amino acids

While NAD+ precursors like NMN or NR directly increase NAD+ synthesis, ergothioneine enhances NAD+ regeneration via enzyme persulfidation

The age-related increase in arborization of the apical tree of xCT +/+ mice -once again an event which was not seen in xCT / mice- was restricted to the mid-apical dendrites ( stratum radiatum ) where the CA1 neurons receive extensive glutamatergic input of the Shaffer collaterals, possibly representing a compensatory reaction induced by excitotoxic damage in the aged hippocampus, as described in ischemia [84]

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, positive interaction where one clone benefits the others) and mutualism (cooperation between populations) [1]