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Many studies show similarities between the symptoms of Vitamin B12 deficiency and multiple sclerosis (MS)

& Roberts, E

10.1038/nature11285 Nature 136 Nour-EldinH

The X-inactive specific transcript ( Xist ), expressed on the inactivated X (Xi) chromosome, plays a key role in X chromosome inactivation (XCI) by forming a unique chromosomal conformation [16, 17], thereby maintaining the balance of sex-linked gene expression [18, 19]

Pharmacokinetic analysis was performed to profile the drug concentrations in both the plasma and brain following intranasal administration of the RBD suspension, RBD-SLN, and RBD-SLN-ISG