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B12 (cobalamin) Perhaps the most well-known of all the B vitamins, B12 is vital for neurological function, DNA production, and red blood cell development

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We were able to resolve high-resolution ligand-bound structures for analogs 43 (ID: pdb_000013CV, 1.95 ), 53 (ID: pdb_000013CW, 2.48 ), 60 (ID: pdb_000013DF, 1.84 ), and 69 (ID: pdb_000035YH, 2.60 ) bound to UCHL3 ( Figure 5 , ligand density in Figure S1 and crystallographic data statistics in Table S1 S3 )

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The fluorescence of A was significantly lower in GO + amlodipine (36%), GO + aminoguanidine (36%), and GO + NAC (49%) than in GO