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GinsbergG.SmolenskiS.NeafseyP.HattisD.WalkerK.GuytonK

Moreover, probiotics have been reported to show their potential role in numerous GIT disorders like inflammatory bowel disease (IBD), gastroenteritis, diarrhea, colitis, celiac disease, and many more (Stavropoulou and Bezirtzoglou, 2020)

Effects seen at those exposures cannot be assumed to occur at physiologic levels, and pushing systemic exposure high enough to reproduce them in a whole organism is precisely what raises the copper-loading concern