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Notably, recent studies have indicated that interactions between microbial communities and ENS development may commence earlier than previously thought, potentially during gestation via maternal microbial metabolites and immune factors transferred through the uteroplacental circulation (110, 111)

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The Nrf2 protein, encoded by the NFE2L2 gene, regulates around 250 genes that play a role in maintaining cellular balance, including antioxidant proteins, detoxifying enzymes, drug transporters, and various cytoprotective proteins [43]

Phytosomes as a plausible nano-delivery system for enhanced oral bioavailability and improved hepatoprotective activity of Silymarin

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