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If confirmed in other cohorts of ALS patients, deficiency of Gpx4 could represent a novel vulnerability of motor neurons in ALS

doi: 10.1038/s43018-024-00749-6 109 MaalejKMMerhiMInchakalodyVPMestiriSAlamMMaccalliCet al

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Various kinases are subsequently recruited and promote the transcription of cytokines, including the multifunctional interferons (IFNs) and pro-inflammatory cytokines [16]

Drugs that cause AIH-like DILI with positive autoantibodies include minocycline, statins, hydralazine, and nitrofurantoin