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Furthermore, as shown in Figure 1C, the important upstream side of the known M pro cleavage site at the nsp13/14 junction, NVATLQ/A, is remarkably similar to that of the active site sequence of GPx1, NVASLU/G, where the selenocysteine (U) lines up with a glutamine (Q) in the viral sequence

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S100A8/S100A9-induced increase in NADPH-oxidase activity is via S100A9 transport of the cofactor arachidonic acid to the NADPH oxidase complex, and interaction of S100A8 with cytosolic phox proteins facilitating the enzyme assembly (114)

Discussion In this study, we demonstrated that the methylotrophic yeast C