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Our results show a statistically significant effect size for deaths in social proximity on OODs in counties in the United States, controlling for spatial proximity, as well as demographic and clinical covariates

The individual variables are also examined in the ANOVA table

2) were intermediate to large, thus explaining 9 to 25% of the variance 31

doi: 10.1038/s41588-019-0350-x 175 SaxenaS.KruysV.De JonghR.VamecqJ.MazeM

Age-related NAD+ decline impairs this critical DNA repair pathway CD38 balance: The ectoenzyme CD38 consumes NAD+ and increases with age, creating a vicious cycle of NAD+ depletion and immune dysregulation By restoring NAD+ levels, supplementation recalibrates multiple aging pathways simultaneously: improved DNA repair, enhanced mitochondrial biogenesis, restored epigenetic regulation, activated autophagy, and improved nutrient sensing