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Melanogenesis is the process by which melanin pigment is produced within specialised cells called melanocytes, located in the basal layer of the epidermis. The process begins when melanocytes are stimulated by internal Full article: Peptide Design for Enhanced Anti Melanogenesis: Optimizing Molecular Weight, Polarity, and Cyclization Natural protection against oxidative stress in human skin melanocytes PMC 50mg Melanotan 2: Safety Facts and Consumer Guidance Pigmentation occurs when melanocytes are overstimulated by factors such as UV exposure, hormones or inflammation. Once triggered, excess melanin is deposited into the skin, creating uneven tone and darkened patches. Effective pigmentation

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