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Prolonged exposure to hypoxia has been shown to induce pulmonary vasoconstriction and pulmonary arterial hypertension, which subsequently results in a sustained elevation of right ventricular afterload, thereby imposing formidable challenges on the structural and functional integrity of the cardiovascular system (3, 4)

However, there are conditions and risk factors that can compromise the endogenous production of glutathione by our liver and which are independent of our age

Professor of Surgery and Medicine, Fienberg School of Medicine Northwestern University Administrative Director, Center for Heart Failure, Bluhm Cardiovascular Institute Northwestern Memorial Hospital Chicago, Ill

Co-expression analysis was performed to identify CERSRLs in differentially expressed (DE) lncRNAs

* These identities were based on exact mass, retention time and MS/MS spectrum