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The next day, the media was removed and 45K ECFCs per well in 50100 L of media was plated on top of the ADSC monolayer and incubated at 37C, 5% CO 2 for 36 hours before the addition of growth factors and inhibitors

Mol Cell 3:465475 Koutnikova H, Campuzano V, Koenig M (1998) Maturation of wild-type and mutated frataxin by the mitochondrial processing peptidase

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Nevertheless, heteroplasmy complicates clinical interpretation, as mutation burdens differ across tissues and tumor subclones, challenging the integration of these data into diagnostic or prognostic models [158]

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