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Nanosight analysis An aliquot of EV samples was diluted 1:100 or 1:1000 in PBS, depending on the number of EV pellets pooled for each experiment

Arterioscler Thromb Vasc Biol 2002

It accumulates in proximal tubular cells, driving iron depletion-induced cell death.87 Precisely because of this proximal tubular cell tropism, it may be tested at lower doses to induce enough iron depletion to prevent ferroptosis