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927 Mechanically, inhibition of HDAC3 leads to increased YAP nuclear translocation through the Hippo pathway, altering hepcidin levels and contributing to ferroptosis induced by iron overload in liver injury

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This might be considered unexpected because these neighboring structures are central to two of the three cytokine-to-brain pathways described in section Inflammation neurocircuitry : the NTS is where vagus nerve enters the brainstem, and area postrema is a key circumventricular organ

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