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This helps ensure maximum absorption of the B12 supplement

14.2 Prevention of Postmenopausal Osteoporosis The efficacy and safety of Reclast in postmenopausal women with osteopenia (low bone mass) was assessed in a 2-year randomized, multi-center, double-blind, placebo-controlled study of 581 postmenopausal women aged greater than or equal to 45 years, who were stratified by years since menopause: Stratum I women less than 5 years from menopause (n=224)

For instance, hospitalized patients with severe alcohol-related malnutrition might receive 1 mL IM daily for a week

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The overwhelming body of research focuses on deficiency-related psychiatric symptoms rather than toxicity or adverse effects from adequate intake