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Another commenter asserted that monitoring a physiological parameter does not inherently translate to improved outcomes unless accompanied by actionable thresholds and validated interventions

Clinical indications include deficiency due to inadequate diet or malabsorption, drug-induced deficiency (for example, from long-term isoniazid or oral contraceptives), and certain inborn errors of metabolism (such as pyridoxine-dependent seizures or sideroblastic anemia)

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If you need dramatic weight loss, GLP-1 agonists like semaglutide or tirzepatide produce 5-10 times greater results through an entirely different mechanism

We suggest that vegetarians and vegans take b12 supplements with cyanocobalamin daily