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These effects extend beyond in vitro experiments

Direct hGH often causes significant edema and water retention

Food Sci Tech Res 20:699703 Shibata M, Hirotsuka M, Mizutani Y, Takahashi H, Kawada T, Matsumiya K, Hayashi Y, Matsumura Y (2017) Isolation and characterization of key contributors to the kokumi taste in soybean seeds

There was a large increase in excretion of uranium, but it was not statistically significant (only 14-15 participants had detectable excretion of uranium before or after taking DMSA)