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In normal human fibroblasts, GHK reduces the secretion of TGF- and inflammatory cytokines, such as TNF- and IL-6, to relieve skin inflammation and prevent the formation of hypertrophic scars (Gruchlik et al., 2012) [8] The treatment of rats, mice, and pigs with GHK effectively activate systemic healing throughout the animal

Cheng B, et al

Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro