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265 Compared to both Fer-1 and Lip-1, lipophilic THNs have similar potency, while hydrophilic THNs are ineffective at inhibiting ferroptosis

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Similarly, other studies have demonstrated a direct association between kidney IGF1R expression and the severity of RCC.41,42In vitro studies using RCC cell lines have shown that treatment with neutralizing antibodies against IGF1R can reduce IGF1R expression and inhibit cell proliferation