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Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications

These data indicate that NO has a substantial impact on the remodeling of glucose oxidation through the TCA cycle in stimulated macrophages (Fig

Artemisinin induces iron- and ROS-dependent cell killing in pancreatic ductal adenocarcinoma cell lines, suggesting that Artemisinin can act as a specific inducer of ferroptosis in pancreatic cancer cells (Sui et al., 2018)

Vitamin C - In 48 individuals with ascorbate deficiency taking 500 or 1000 mg per day of vitamin C for 13 weeks led to an 18% increase in lymphocyte Glutathione levels

Interestingly, it was shown that the tumor suppressor p53 also induced GLS2 expression in response to DNA damage or oxidative stress and thus promoted the glutamine metabolism and decrease ROS levels