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Potisate Y, Phoungchandang S, Kerr WL

Abstract The global shortage of suitable donor kidneys is the primary challenge in kidney transplantation, and it is exacerbated by ageing donors with increased numbers of health issues

Athletes often use glutathione or NAC to help support the body's natural recovery processes and maintain cellular integrity after a tough workout

Figure 1 (B) NETs induce glioma cells to secrete IL-8 to recruit neutrophils, promote the CXCR2/PI3K/AKT/ROS signalling axis, and finally promote the formation of NETs, forming a positive feedback pathway ( (C) Cytokines and growth factors, such as granulocyte-macrophage colony stimulating factor (GM-CSF), granulocyte colony stimulating factor (G-CSF), IL-2, IL-1, IL-6, and VEGF, can induce the aggregation of MDSCs in tumour hosts (102, 103)

With continued exploration, this could be established as a safer drug to improve the lives of patients