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443 The differentiation and phenotypic polarization of macrophages are influenced by their interactions with MSCs, which secrete factors such as PGE2, IDO, IL-10, and TGF-

the hypervariable regions in each chain are held together in close proximity by the FRM and, with the hypervariable regions from the other chain, contribute to the formation of the antigen-binding side (see Kabat et al., loc

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Blockage of Glyoxalase I Inhibits Colorectal Tumorigenesis and Tumor Growth via Upregulation of STAT1, P53, and Bax and Downregulation of c-Myc and Bcl-2