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It is also important to be aware of symptoms that may suggest either worsening B12 deficiency or poorly controlled blood glucose, and to seek prompt medical advice if you experience: Persistent fatigue, breathlessness, or pallor (possible anaemia) Tingling, numbness, or weakness in the hands or feet (possible B12-related neuropathy) Unsteadiness when walking, or changes in memory or thinking (possible signs of more severe B12 deficiency requiring prompt assessment) Increased thirst, frequent urination, or unexplained weight loss (possible hyperglycaemia) If you think you may be experiencing a side effect from a medicine for example, symptoms of B12 deficiency that you believe may be related to metformin you or your healthcare professional can report this via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk

2 In many cases, healthcare providers may recommend vitamin B12 supplementation or cobalamin injections to help restore healthy levels

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UNDERSTANDING PUBERTY THE IMPORTANCE OF STATISTICS IN HEALTHCARE JOURNAL SCAN: A REVIEW OF 44 RECENT PAPERS OF IMMEDIATE CLINICAL SIGNIFICANCE, HARVESTED FROM MAJOR INTERNATIONAL JOURNALS DIAGNOSTIC IMAGE PRE-OPERATIVE CHAPTERS 15 AND 16 LEARNING FROM EXPERIENCE CHAPTER 8