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Aug 2017;17(8):687-692

doi: 10.1158/1538-7445.AM2024-CT008

Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins

Biochemistry (Moscow) 82 , 10791087

IPP and dimethylamine pyrophosphate (DMAPP) serve as substrates for farnesyl diphosphate synthase (FDPS), to generate both geranyl pyrophosphate (GPP) and farnesyl pyrophosphate (FPP), which can be converted into squalene, a long-chain molecule that represents a key step in cholesterol synthesis