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PMID: 35786294 Adv Sci (Weinh) Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

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naked DNA can be delivered by the use of liposomes which fuse with the cellular membrane or are endocytosed, i.e., by employing ligands attached to the liposome, or attached directly to the DNA, that bind to surface membrane protein receptors of the cell resulting in endocytosis

concluded that anthocyanins could alleviate renal injury in DKD by upregulating taurine, Trp, and tyrosine pathways through histological analysis of kidney and serum in mice (81)