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Necrotic death leads to the leakage of intracellular oxidative and inflammatory components, which then propagate more inflammation, oxidative stress, and death in neighboring cells (Figure 5) (173)

ChAdOx vaccines have been proven to elicit particularly strong T cell responses (33), biased toward IFN secretion and a Th1-phenotype

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In addition, Mn is involved in the synthesis and activation of many enzymes and in the regulation of glucose and lipid metabolism

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