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Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan ligand 383 Purity (HPLC) >= 95%

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan ligand 383 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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Description

383 Purity (HPLC) >= 95% Solubility DMSO

It has been predominantly used to develop a variety of green fluorescent peptides that can be excited with the 488 nm line of the Ar laser

NCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

214 Purity (HPLC) >= 95% Solubility DMSO

Product Name DOTA-tris(t-Bu)ester-PEG2-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C34H64N8O9 Molecular Weight 728

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-Exatecan ligand 383 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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