Excessive ROS production leads to detrimental effects on mitochondrial proteins and lipids, causing oxidative damage and facilitating ferroptosis ( The underlying cause of ferroptosis is a disequilibrium between the bodys oxidants and antioxidants
Citt Della Salute e Della Scienza Di Torino, University of Turin, Turin, Italy, (4)University of Milano-Bicocca, (5)Division of Hepatology, Ospedale San Giuseppe, Universit Di Milano, (6)Translational and Precision Medicine, Sapienza University of Rome, Italy, (7)Department of Translation and Precision Medicine, Sapienza University of Rome, Rome, Italy, (8)Humanitas University, Rozzano (MI), MI, Italy, (9)Humanitas University, Rozzano (Milan), Italy, Division of Internal Medicine and Hepatology, Humanitas Clinical Research Center Ircss, (10)Division of Gastroenterology and Hepatology, Foundation Irccs Ca Granda Ospedale Maggiore Policlinico, Milan, Italy, (11)Hepatology and Gastroenterology, Asst GOM Niguarda, (12)University of Genova, Genova, Italy, (13)Ospedale Policlinico San Martino, Genova, (14)Gastroenterology Unit, Santa Maria Delle Croci Hospital, Ravenna, Italy, (15)Division of Gastroenterology, National Institute of Gastroenterology S De Bellis, Castellana Grotte, Bari, Italy, (16)Fondazione a Gemelli Hospital Irccs, Internal Medicine, Gastroenterology, Hepatology, (17)Gastroenterology Unit, Fondazione Casa Sollievo Della Sofferenza Irccs San Giovanni Rotondo, (18)Gastroenterology Unit, Fondazione Casa Sollievo Della Sofferenza Irccs, San Giovanni Rotondo (Foggia), Italy, (19)Internal Medicine, Asst Lecco Hospital, (20)University of Cagliari, (21)Internal Medicine, Ospedale Barletta, (22)Hepatology Unit, Pescara General Hospital, (23)Liver Unit, Arnas Garibaldi, Catania, Italy, (24)Gastroenterology and Hepatology Unit, Policlinico-Vittorio Emanuele, (25)Hospital Universitario 12 De Octubre, Madrid, (26)Hospital Universitario Reina Sofia, Cordoba, (27)Complexo Hospitalario Universitario De Santiago, Corua, (28)Madrid, (29)Spain, (30)Hospital Universitario La Fe, Valencia
Jenssen M, Furberg AS, Jorde R, Wilsgaard T, Danielsen K
Wired for threat: clinical features of nervous system dysregulation in 80 children
Boroughs LK, DeBerardinis RJ
