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Instead, inulin supplementation, in a microbiome-dependent manner, drastically increases Phgdh and Psat1 , the key de novo serine synthesis pathway enzymes

Lacerda et al

Wang YC, Kong WZ, Jin QM, Chen J, Dong L

& Brent, G

These disruptions may suggest a reduced ability of mitochondria to generate sufficient energy to meet cellular demands, particularly in tissues with high energy requirements like muscles and connective tissues