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The total number of 1131 fasting blood samples were collected from 243 track and field athletes, covering 904 samples from 189 strength athletes (age 23 1 yr., body mass 79 2 kg, height 181 1 cm, BMI 24.5 0.6 kg/m 2 ) and 227 samples from 54 endurance athletes: (age 25 1 yr., body mass 61 1 kg, height 175 1 cm, BMI 19.9 0.2 kg/m 2 )

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The C-terminal segment of the pro-domain (L 113 P 128 ) is flexible and occupies the catalytic cleft in a substrate-like conformation, thereby blocking access

Oxidation targets vulnerable amino acids, particularly methionine residues