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Higher pain perception and lack of recovery from neuropathic pain in females: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice

Datis Kharrazian is a Harvard Research fellow in immunity, has a PhD in Health Science and is most exciting for me, he is a chiropractor

The Wnt/-catenin pathway enhances regulatory effects of Nurr1, including TH promoter activation, indicating that Nurr1 is a key determinant of VTA DA neurotransmitter identity by controlling genes involved in DA synthesis, vesicular packaging, axonal transport, and reuptake (Jankovic et al., 2005)

They especially lack mitochondrial ISC-containing subunits of respiratory chain complexes I, II and III and aconitase activities

Regulatory pathways are also becoming clearer