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This review will first highlight the pathophysiological mechanisms underlying the onset and progression of ADRD

Cell viability assay Cell viability was measured by a colorimetric cell viability kit (Promokine, Heidelberg, Germany) with the tetrazolium salt WST-8 (2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt), which can be bioreduced to a water-soluble orange formazan dye by dehydrogenases present in the viable cells

Nat Rev Dis Prim 1:118 Wang X, Deng J, Yuan J, Tang X, Wang Y, Chen H, Liu Y, Zhou L (2017) Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells

This is further evidenced by a significant increase in recycled SAM post-RT (Fig