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Leucine carboxyl methyltransferase downregulation and protein phosphatase methylesterase upregulation contribute toward the inhibition of protein phosphatase 2A by alpha-synuclein

Preclinical studies have demonstrated that FMT benefits DKD models by restoring gut microbiota composition, enhancing microbial diversity, and reducing tubulointerstitial injury and inflammatory cytokines [209]

These findings indicate that MSG may trigger oxidative stress by suppressing the expression and activity of thioredoxin reductase, an important antioxidant enzyme in the liver

309:570577, 2013 [DOI] [PMC free article] [PubMed] [Google Scholar] 78.James SJ, Melnyk S, Jernigan S, et al

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