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Nevertheless, the mean age at death for individuals born between 1985 and 1999 has been 29 years, and earlier diagnosis by newborn screening, treatment with more palatable cystine-depleting agents, and trials with gene therapy are critical current pursuits

Lan Y, Wu X, Ni L, Liu Y, Yan T, Duan D, et al

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Navalpakam A, Thanaputkaiporn N, Poowuttikul P (2022) Management of anaphylaxis

Twice-daily dosing has been used in some acute-phase protocols where intensive early exposure is the design goal