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Description

EMMPRIN promotes angiogenesis through hypoxia-inducible factor-2alpha-mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2

However, there are also generic oral versions available, but their effectiveness is mostly unknown

Reported laboratory work covers its involvement in signalling pathways including sirtuins, poly(ADP-ribose) polymerases (PARPs) and cyclic ADP-ribose-generating enzymes linked to DNA repair, chromatin regulation and calcium signalling