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Nutrients 13 (8), 2802 (2021)

Substrate specificity combined with stereopromiscuity in glutathione transferase A4-4-dependent metabolism of 4-hydroxynonenal

Sub-group analyses supported the use of omega-3 fatty acids (SMD = 0.14, 95% CI = 0.27 to 0.02, p = 0.03) and botanical drug or dietary intervention (SMD = 0.86, 95% CI = 1.58 to 0.13, p = 0.02) among older participants

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LC two-sided t-test CD4 T cells p = 0.0076, CD8 T cells p = 0.0182, CD19 B cells p = 0.0842), compared to healthy controls (Supplementary Figure S2)